A medicine used to relieve occasional mild to moderate pain such as headache, dental, menstrual, muscle or back pain, as well as feverish conditions.
Contains 20 granulated sachets for oral solution.
Ibuprofen is a medicine commonly known as ibuprofen, which is used to reduce pain and fever. It is indicated for adults and adolescents aged 12 years and over (weighing 40 kg or more) for the symptomatic relief of occasional mild to moderate pain, such as headaches, dental, menstrual, muscular (contractures) or back pain (lumbago), as well as febrile states.
Adults and children over 12 years of age or weighing 40 kg or more.
This medicine is taken orally. Add the entire contents of one sachet to a glass of water and then drink it. It is recommended that you take this medicine with meals or with milk, especially if you experience digestive problems.
The suggested dose is:
In adults and adolescents over 12 years of age who weigh 40 kg or more: If necessary, take one sachet of 400 mg ibuprofen every 6 to 8 hours. Do not take three sachets (1,200 mg of ibuprofen) in a single day.
Older patients: The doctor will determine the dose because a reduction from the usual dose may be needed.
patients with kidney, liver or heart disease
Always use the lowest dose that is effective. The administration of this medicine is subject to the onset of pain or fever. As soon as the pain or fever disappears, the medicine should be stopped. reduce the dose and consult a doctor. Always use the lowest effective dose. The medicine is taken only as long as pain or fever persists, and should be discontinued once these symptoms have subsided.
Do not take Ibuphen 400:
If you are allergic to ibuprofen or any of the other ingredients of this medicine. Reactions indicating allergy could be: itchy rash, swelling of the face, lips or tongue, runny nose, difficulty breathing, bronchospasm or asthma.
If you have severe kidney or liver disease.
If you have had an ulcer or bleeding in your stomach or duodenum, or if you have had a perforation in your digestive tract.
If you vomit blood.
If you have dark stools or bloody diarrhoea.
If you have cerebrovascular or other active bleeding.
If you have blood clotting or bleeding problems or are taking anticoagulants (medicines that "thin" the blood). Your doctor will carry out blood clotting tests if you need to use anticoagulants at the same time.
If you have severe heart failure.
If you are experiencing severe dehydration caused by vomiting, diarrhoea or inadequate fluid intake.
If you are in the third trimester of pregnancy.
This medicine may cause side effects, although not all patients will experience them.
In short courses, the likelihood of side effects is lower if the daily dose is below the maximum recommended dose. The following effects have been documented:
Exacerbation of infection-related inflammation (e.g. development of necrotising fasciitis), coinciding with the use of non-steroidal anti-inflammatory drugs.
Aplastic anaemia (failure of the bone marrow to produce different types of cells).
Decreased platelets, decreased white blood cells (may be manifested by fever, chills or sore throat), decreased red blood cells (may be manifested by shortness of breath and pale skin), decreased granulocytes (a type of white blood cells that may predispose to infection).Fever, sore throat, superficial sores in the mouth, flu-like symptoms, extreme tiredness, nosebleeds and skin bleeds are the first symptoms. bleeding time may increase.
Allergic reaction, hypersensitivity reactions with rash and itching, as well as asthma attacks (possibly together with a drop in blood pressure).
Anaphylaxis (generalised allergic reaction).
Severe hypersensitivity reactions (these may be characterised by swelling of the face, tongue and larynx with bronchospasm, dyspnoea, tachycardia and hypotension which may include life-threatening shock).
Insomnia, anxiety, restlessness.
Psychotic reaction, nervousness, irritability, depression, confusion, disorientation.
Fatigue or drowsiness, headache and dizziness or feeling of instability.
Insomnia, excitement, irritability.
Paraesthesia (sensation of numbness, tingling, tingling, cramping, etc. more frequent in hands, feet, arms or legs).
Aseptic meningitis. In most cases where aseptic meningitis has been reported with ibuprofen, the patient had some form of autoimmune disease (such as systemic lupus erythematosus or other collagen diseases) which was a risk factor. Symptoms of aseptic meningitis observed were neck stiffness, headache, nausea, vomiting, fever or disorientation.
Vision disturbances.
Abnormal or blurred vision.
Papilledema (inflammation of the optic nerve).
Vertigo
ringing or buzzing in the ears.
hearing impairment
Palpitations, heart failure.
Heart failure and chest pain, which may be a sign of a potentially serious allergic reaction called Kounis syndrome.
High blood pressure.
Arterial thrombosis.
Asthma, aggravation of asthma, bronchospasm, dyspnoea (shortness of breath).
Throat irritation.
Peptic ulcers, gastrointestinal bleeding, perforations (in some cases fatal), especially in elderly patients.
Gastrointestinal discomfort such as heartburn, reflux, abdominal pain, nausea, vomiting, flatulence, diarrhoea, constipation and slight gastrointestinal bleeding which may cause anaemia in exceptional cases.
Gastrointestinal ulcers, potentially with bleeding and perforation, ulcerative stomatitis, exacerbation of colitis and Crohn's disease, melena (blood in stool), gastritis.
Vomiting blood.
Inflammation of the oesophagus, pancreatitis, intestinal stenosis.
Anorexia
liver damage, hepatitis (inflammation of the liver), liver function abnormalities and jaundice (yellowing of the skin and eyes).
Skin rash.
Reddening of the skin, itching or swelling of the skin, purpura (purplish patches on the skin).
Anaphylactic reaction.
Medicines such as ibuprofen (arginine) may be associated, in very rare cases, with very severe blistering reactions such as Stevens-Johnson syndrome (disseminated erosions involving the skin and two or more mucous membranes and mucosal lesions).(disseminated erosions affecting the skin and two or more mucous membranes and purple lesions, preferably on the trunk) and toxic epidermal necrolysis (erosions on mucous membranes and painful lesions with necrosis and detachment of the epidermis). Hair loss, erythema multiforme (skin lesion). Exceptionally, severe skin infections and soft tissue complications may occur during chickenpox.
Skin becomes sensitive to light (photosensitivity), aggravation of skin reactions.
Haematuria (presence of blood in the urine).
Oedema (signs which may be indicative of renal disease, sometimes including renal failure); renal tissue damage (papillary necrosis), increased serum uric acid concentration.
Based on experience with NSAIDs in general, interstitial nephritis, nephrotic syndrome and renal failure cannot be excluded.
Aggravation of inflammations during infectious processes.
Oedema
Anti-inflammatory/analgesic drugs such as ibuprofen may be associated with a small increased risk of heart attack or stroke, especially when used in high doses. Do not exceed the recommended dose and duration of treatment. You should not take more than 3 sachets of granules (1200 mg ibuprofen) a day, to avoid possible heart or circulatory problems.
Talk to your doctor in any of the following cases
Signs of allergic reaction to ibuprofen have been reported with this medicine, such as breathing problems, swelling of the face and neck region (angioedema), and chest pain. Stop using Ibuphen Xp immediately and contact your doctor or the emergency medical service immediately if you notice any of these signs.
It is advisable not to take this medicine if you have chickenpox.
Stop taking this medicine and see a doctor immediately if you develop any rash, mucous membrane lesions, blisters or other signs of allergy, as these may be the first signs of a very serious skin reaction.
Skin reactions: Serious skin reactions have been reported, including exfoliative dermatitis, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis, drug reaction with eosinophilic eosinophilism, and other serious skin reactions.In association with ibuprofen treatment, discontinue treatment with ibuprofen and discontinue treatment with ibuprofen. Discontinue treatment with Ibuprofen Xpress and seek medical attention immediately if you notice any of the symptoms associated with these serious skin reactions.
Allergic reactions are possible with this medicine. Treatment should be stopped if redness and swelling or injury of the skin occurs.
If you experience visual disturbances during treatment with ibuprofen, discontinue treatment and consult your doctor for an eye examination.
If you suffer from headaches after prolonged treatment, you should not take higher doses of the medicine.
If you have acute intermittent porphyria (a metabolic disease that affects your blood and may cause symptoms such as reddish urine, blood in urine or liver disease) to assess whether or not you should take ibuprofen.
If you have systemic lupus erythematosus (a chronic disease that affects the immune system and can affect various vital organs, the nervous system, blood vessels, skin and joints), you may need to take ibuprofen.Aseptic meningitis (inflammation of the meninges, the membranes that protect the brain and spinal cord, not caused by bacteria) may occur.)
If you are being treated with diuretics (medicines for urination) because your doctor must monitor your kidney function.
If you suffer from Crohn's disease (a chronic disease in which the immune system attacks the intestine causing inflammation, usually resulting in bloody diarrhoea) or ulcerative colitis as medicines such as ibuprofen may worsen these conditions.
If you are simultaneously taking medicines that alter blood coagulation, such as oral anticoagulants, antiplatelet agents such as acetylsalicylic acid. You should also discuss the use of other medicines that could increase the risk of such haemorrhages, such as corticoids and selective serotonin reuptake inhibitor antidepressants.
If you have an infection.
If you have had or develop an ulcer, bleeding or perforation in the stomach or duodenum, which may be manifested by severe or persistent abdominal pain and/or black stools, or even without previous warning symptoms. This risk is higher when using high doses and prolonged treatment, in patients with a history of peptic ulcer and in elderly patients. In these cases, your doctor will consider the possibility of adding a stomach-protecting medicine.
If you develop symptoms of dehydration, e.g. severe diarrhoea or vomiting, drink plenty of fluids and contact your doctor immediately, as ibuprofen in this particular case may cause kidney failure as a result of dehydration.
If you have kidney or liver disease, are over 60 years of age or need to take the medicine for a long time (more than 1 to 2 weeks), your doctor may need to check you regularly. Your doctor will tell you how often you should be checked.
Ibuprofen may hide the signs of an infection, such as fever and pain. Therefore, this medicine may delay the proper treatment of the infection, which may increase the risk of complications.
If you have asthma or any other breathing disorder.
If you have or have ever had a heart condition or high blood pressure.
If you have oedema (fluid retention).
The active substance is ibuprofen. Each sachet contains 400 mg ibuprofen as ibuprofen (arginine).
The other ingredients (excipients) are: L-Arginine, aspartame (E-951), sucrose, saccharin sodium (E-954), sodium hydrogencarbonate (E-500), peppermint flavouring, anhydrous colloidal silica and sodium lauryl sulphate.
A doctor should be consulted if the condition worsens or does not improve, if fever persists for more than three days, or if pain persists for more than three days in adolescents or five days in adults.
It is recommended to be taken with food to avoid an empty stomach. Consult our pharmaceutical team for help with any questions you may have about this product.
The price of non-prescription medicines is established by law. However, at Farmaciasdirect you can obtain Ibufén Xpress 400 Mg, 20 sachets granulated for oral solution with up to a 10% discount, which is the legal maximum allowed.