Salvacoline is a medicine whose active ingredient is loperamide, an anti-diarrhoeal drug that acts to reduce bowel movement. This allows the contents of the bowel to move more slowly, which in turn facilitates greater absorption of fluids and electrolytes, contributing to a firmer stool consistency. Salvacoline is indicated for the treatment of acute diarrhoea and can also be used in cases of chronic diarrhoea associated with inflammatory bowel diseases.
The main action of Salvacoline is to slow down intestinal transit, which reduces liquid and frequent stools, providing rapid relief. However, its prolonged use without medical supervision is not recommended, as it treats the symptoms and not the underlying cause of diarrhoea.
Indications and appropriate use of Salvacoline
Acute and chronic diarrhoea
Salvacoline is effective in the treatment of acute non-specific diarrhoea and chronic diarrhoea associated with conditions such as irritable bowel syndrome or ulcerative colitis. In acute diarrhoea, its use can rapidly improve quality of life by reducing the urgency of bowel movements and the risk of dehydration. However, in cases of severe diarrhoea, with blood in the stool or high fever, it is essential to consult a doctor before using this medicine, as specific treatment for the underlying infection or inflammation may be necessary.
In addition, Salvacoline should not be used in people with certain serious intestinal conditions such as pseudomembranous colitis or toxic megacolon, as it may worsen the condition.
Recommended dose of Salvacoline
The usual adult dose for acute diarrhoea is two tablets (4 mg) as an initial dose, followed by one tablet (2 mg) after each diarrhoeal stool. The maximum daily dose should not exceed 8 tablets (16 mg) per day. In children over 12 years of age, the starting dose is one tablet (2 mg), and is adjusted according to the child's weight. For children weighing more than 47 kg, a maximum of 7 tablets per day is allowed.
It is important not to exceed the recommended doses and to discontinue treatment if no improvement is seen within 48 hours. In patients with hepatic impairment, it is essential to adjust the dose and to consult a doctor before starting treatment with loperamide, due to the slow metabolisation of the drug in these cases.
Side effects and warnings
The use of Salvacoline may cause mild side effects such as constipation, nausea and drowsiness. In more serious, but rare cases, allergic reactions, dizziness, severe abdominal pain, and cases of dilatation of the colon (megacolon) have been reported, especially in people with inflammatory bowel disease. It is essential to discontinue treatment and consult a doctor if severe symptoms are experienced.
Among the important warnings, Salvacoline is not recommended for use in pregnant or breastfeeding women without consulting a doctor, as small amounts of the drug can pass into breast milk. In addition, avoid operating heavy machinery or driving if treatment causes drowsiness or dizziness.
Interactions with other medicines
Salvacoline may interact with other drugs, which could increase the risk of side effects. Some drugs that could cause interactions are:
- Antibiotics: They can worsen diarrhoea related to antibiotic use.
- Opioids: When combined with opioid painkillers, Salvacoline may increase the risk of severe constipation and central nervous system depression.
- St. John's wort and other herbal remedies: these may alter the effectiveness of loperamide.
For this reason, it is essential to inform your doctor about any other medicines or supplements you are taking before starting treatment with Salvacoline.
Additional recommendations for the use of Salvacoline
Salvacoline is an effective tool for relieving the symptoms of diarrhoea, but should not be used as a prolonged treatment without medical supervision. In cases of persistent or recurrent diarrhoea, the underlying cause should be investigated. It is also essential to stay hydrated while using the medicine, especially in cases of acute diarrhoea, to prevent dehydration.
