Shake before using the serum in the morning and/or evening on cleansed skin of the face and neck. Daily use of antioxidants and photoprotection is recommended to improve the results of the depigmentation treatment. The depigmentation peeling should be performed 1-2 times a week. Apply to clean, dry skin with a gentle, continuous circular motion for 30 to 60 seconds. Leave to act for 20 minutes or overnight. If irritation appears, remove immediately. After the indicated time rinse with plenty of water. Then apply your usual depigmentation treatment.