If you are known to be allergic to any of the components of Oftaclean wipes, it is recommended that you avoid using them. Or, if you have a serious eye infection such as bacterial conjunctivitis, corneal ulcer or other condition requiring specific medical treatment, Oftaclean wipes should be avoided as the sole method of treatment. Finally, if you have an eye injury, such as a wound, corneal abrasion or burn, it is important to avoid using Oftaclean Wipes on the affected area.