Calmagrip Forte 10 Sachets

Calmagrip Forte is a combination of paracetamol (an analgesic that reduces pain and fever), chlorphenaminamaleate(an antihistamine that relieves runny nose) and caffeine. Its use is indicated for the symptomatic relief of catarrhal and influenza processes with fever, mild or moderate pain (such as headache), tearing and sneezing .

Suitable for use in adults and adolescents from 14 years of age.

The contents of the sachet should be taken dissolved in half a glass of water. The recommended dosage varies according to the age of the patient:

• Adults and adolescents over 14 years of age:1 sachet every 6 - 8 hours. Do not take more than3 g per 24 hours (1 day).
• Over 65 years of age: Before taking this medicine you should consult your doctor because you may need lower doses as you are more sensitive to the adverse effects of chlorphenamine.

Patients with kidney or liver disease should consult their doctor before taking this medicine.

Aswith all medicines, Calmagrip Forte may cause side effects, although not everybody gets them.

Because of its paracetamol content, in rare cases, the following may occur: Kidney disorders, cloudy urine, allergic dermatitis (skin rash), jaundice (yellowing of the skin), blood disorders (agranulocytosis), and other side effects.(agranulocytosis, leukopenia, neutropenia, thrombocytopenia, haemolytic anaemia) and hypoglycaemia (low blood sugar). Paracetamol can damage the liver when taken in high doses or in prolonged treatment. Serious skin reactions have been reported very rarely.

The following adverse effects have been observed during the period of use of chlorphenamine, the frequency of which could not be established with certainty:drowsiness, sedation,dry mouth and throat (these effects are more likely to occur in elderly patients),gastrointestinal discomfort, nausea, vomiting, diarrhoea, constipation (these effects can be avoided by taking the medicine with milk or food),skin rashes.

Rarely observed cases of: blurred vision, confusion, urinary retention, difficulty or pain during urination, (these especially in elderly patients), loss of appetite. A paradoxical effect of excitement, nervousness,nightmares may also occur, which has been observed more frequently in children and elderly patients. Blood disturbances, increased sweating, tachycardia.

During the periodof caffeine use, the following adverse effects have been observed, the frequency of which cannot be established with certainty:nervousness, restlessness, irritation of the stomach or intestine, tachycardia.

Sodium saccharin and sodium cyclamate provide 18.8 mg sodium.